Fatal cytotoxic cutaneous lymphoma presenting as ulcerative psoriasis.

نویسندگان

  • Roger H Weenig
  • Nneka I Comfere
  • Lawrence E Gibson
  • Javier Alonso-Llamazares
  • Mark D P Davis
  • Mark R Pittelkow
  • Rokea A el-Azhary
چکیده

BACKGROUND Psoriasis is a common, nonulcerative skin disorder. OBSERVATIONS We describe 3 men recently referred to our institution for evaluation and treatment of severe, ulcerative psoriasis that ultimately was determined to be aggressive, cytotoxic, cutaneous lymphoma. Each had a history of relatively indolent, nonulcerative patches and plaques (duration, 2-45 years) that changed to ulcerated lesions; these rapidly progressed and eventuated in death. CONCLUSIONS The clinical characteristics of the skin lesions and the histopathologic findings form a distinct and rare presentation of cutaneous lymphoma. The initial course is similar to that of mycosis fungoides but eventuates in a highly aggressive disease with fatal outcome.

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عنوان ژورنال:
  • Archives of dermatology

دوره 145 7  شماره 

صفحات  -

تاریخ انتشار 2009